Speakers - João B. Fernandes

Type of the Presentation: Short lecture




João B. Fernandes1, Moacir R. Forim1, Maria Fátima G. F. Silva1, Paulo C. Vieira1, Rose M. Carlos1, Quezia B. Cass1, Arlene G. Correa1, André Rodrigues2, Fernando C. Pagnocca2, Odair C. Bueno2,  Marisa N. Fernandes3, Carmen L. Cardoso4
1Dep. Quím., Univ. Fed. de S. Carlos – UFSCar, Rod. Washington Luís, Km 235- SP-310, CEP 13565-905, São Carlos, SP, Brasil. Email: djbf@ufscar.br.  2CEIS – Centro de Estudos de Insetos Sociais, UNESP – Univ. Est. Paulista "Júlio de Mesquita Filho - Campus Rio Claro, Av. 24ª, nº 1515, CEP 13506-900, Rio Claro-SP, Brasil.  3Dep. de Ciências Fisiol. – Univ. Fed. de S. Carlos – UFSCar, Rod. Washington Luís, Km 235- SP-310, CEP 13565-905, São Carlos, SP, Brasil. 4Fac. de Fil., Ciências e Letras de Rib. Preto, Univ. de S. Paulo, Rib. Preto,14040-901, São Paulo, Brasil.


Correspondence: djbf@ufscar.br


The control of insect pests (such Plutella xylostella, Spodoptera frugiperda, Diatraea saccharalis, Bemisia tabaci, Plutella xylostella, Aedes aegypti), and with emphasis to Atta sexdens rubropilosa, which are dominant herbivores of the tropical region, stored grain pests and disease transmitters and that cause serious damages to the Brazilian economy, has been made using synthetic insecticides. Most of these compounds are non-specific, toxic to man and to the environment and promote the emergence of resistance by insects. In the mechanisms of the insecticidal action are involved several routes with participation of enzymes.

Based on this information, studies to obtain, to express and inhibition of these enzymes (pectinase and amylase of the fungus Leucoagaricus gongylophoros, symbiote of Atta sexdens rubropilosa and ant acetylcholinesterase) have been developed by the DQ-UFSCar Group of Natural Products for extracts, pure natural compounds and metallic complexes of them, aiming the control of insect pests. These assays utilize immobilization of the enzymes in chromatographic columns and microelectrodes. Nanoencapsulation of the most active compounds and the complexation of natural products with metals lead to greater action and greater stability of the insecticides, fungicides and bactericides. Studies in these subjects are also under development and previous results indicate an improvement in their action against the leaf-cutting ants, its symbiotic fungus and others insects.

In honor of Dr. José Tércio Barbosa Ferreira

Sao Paulo Research Foundation - FAPESP - Proc. 2012/25299-6